8-Day Healthy Aging Retreat

This 8-day retreat highlights the neuroprotective and physical health benefits of psilocybin and DMT. While open to all, it is designed with the more mature guest in mind, creating a space where brain health and aging well are central. Expect a thoughtful community, discussions on longevity, and practices that use psychedelics to support a vibrant, extended healthspan.

Exclusively Private Rooms

All prices are based on single occupancy. Add a second participant to your room for $2,950, which includes all retreat activities and services. Airport transport is included.

$6,875 USD
Standard Room
$7,275 USD
Premium Room
$7,750 USD
Ultra Premium Room

At Eleusinia, you start your journey with our 10-point preparation checklist. We’re strong advocates for the power of education in preparing for your psychedelic experience. Our preparation materials provide detailed insights into the neuroscience and mechanisms behind these substances. Aside from education, our process includes coaching you on neuroscience-based skills, techniques, and exercises to help you productively navigate your sessions.

The Healthy Aging retreat highlights psilocybin’s neuroprotective and anti-aging potential through carefully guided macrodose experiences. Guests participate in two macrodose sessions, each designed to help sustain the long-term benefits of psychedelics by building comfort, safety, and skill in navigating these powerful states. Having a comfortable and manageable macrodose experience is essential for long-term practice. Without learning how to confidently navigate these sessions, it would be difficult to engage in the kind of ongoing maintenance that contributes to lasting results.

Recent studies suggest that psilocybin may extend cellular lifespan and perhaps even lengthen telomeres, making it a potentially powerful tool for extending healthspan. The exact mechanism is not yet fully understood, but researchers believe it is connected to psilocybin’s anti-inflammatory properties. These unique anti-inflammatory effects target specific inflammatory markers that are linked to age-related neurodegenerative decline and the hardening of arteries. Since these effects are relatively short lived and cumulative, regular maintenance may be necessary to maximize their potential benefits.

The therapeutic value of psilocybin lies not only in its physical benefits, but also in its ability to sharpen our appreciation for the ordinary, transforming simple details such as textures or the movement of leaves into captivating experiences. At Eleusinia, these sessions are held in the open spaces of our gardens, where nature supports both relaxation and depth of insight while maintaining privacy and safety.

Each macrodose session lasts 4 to 6 hours and is tailored to the individual, with dosage and guidance adjusted to optimize both immediate impact and long-term benefits. After the first session, our team conducts a thorough review of each guest’s experience, including intensity, physical sensations, and emotional tone, so the second session can be carefully refined to match personal needs.

By combining macro and mini-dosing, the retreat offers a well-rounded approach that not only strengthens brain health but also equips participants with practical tools to integrate psychedelics into their ongoing lives. This approach is especially supportive for those seeking to maintain cognitive resilience and vitality as they age.

The DMT experience is profoundly psychedelic, marked by sensations and visual phenomena that often defy description. As a non-specific amplifier, DMT enhances and alters multiple dimensions of consciousness, including auditory, visual, emotional, and somatic perception. While certain themes may recur, each session is uniquely personal and often becomes a powerful reference point for future practice.

What makes DMT particularly valuable in the context of healthy aging is its strong impact on Sigma-1 receptors, which enhances its anti-inflammatory and neuroprotective effects. These effects target the age-related inflammation that contributes to brain fog, cognitive decline, and even the everyday aches and pains many people have come to accept as normal parts of aging. By addressing these markers directly, DMT supports both mental clarity and physical resilience.

Because DMT is too delicate to survive digestion, it is vaporized and inhaled rather than consumed orally. This method allows the compound to take full effect within minutes. To make the process comfortable and efficient, our team provides careful coaching on how to vaporize and inhale properly, ensuring each guest can engage fully and comfortably.

At Eleusinia, DMT sessions are conducted individually with two facilitators present, ensuring safety and full immersion. Each session lasts approximately 10 to 15 minutes and is free from external distractions. Despite their brevity, these sessions are often described as among the most powerful and memorable parts of the retreat, offering both immediate clarity and long-term therapeutic value.

Another advantage of DMT is that, unlike psilocybin, it does not build short-term tolerance. This allows guests to engage with it more frequently during the retreat, making it an effective tool for maintaining sensitivity and reinforcing the benefits of other psychedelic sessions. For those focused on aging well, this means DMT can serve as a practical way to sustain progress, keep the mind sharp, and support ongoing vitality.

The psychedelic experience is often likened to a dream-like state. Like dreams, these experiences can be profound, insightful, and revelatory, yet they can also be confusing, contradictory, and even challenging or frightening. Integration is the process of documenting, interpreting, and deriving meaning from these experiences so that they aren’t simply forgotten, much like fleeting dreams. More importantly, integration acknowledges that these altered states are not an ultimate destination, but rather a complex part of a larger subconscious and therapeutic journey.

At Eleusinia, we take a holistic approach to integration, focusing on three key dimensions: psychological, spiritual, and somatic. Following a macrodose experience, our practitioners engage in personalized one-on-one integration sessions with each guest, guiding them through reflection and helping them document, remember and extract personal meaning from their psychedelic journey. Our practitioners also use these sessions to assist those who have had challenging experiences, helping them reflect, contemplate and develop approaches in tackling future experiences. These integration meetings can also be recorded, allowing guests to document and revisit their reflections later or to share them with their therapist back home.

For those interested in a spiritual perspective, we offer individual integration sessions with our curandera, who provides spiritual insights and draws from traditional Mexican spiritual mushroom practices. Additionally, we provide group meditation coaching that emphasizes somatic awareness and mindfulness as part of the integration process.

Functional magnetic resonance imaging (fMRI) studies show notable similarities between brain activity during meditation and psychedelic states. Put simply, psychedelics can provide a glimpse of what deep meditation feels like, often making the practice more accessible and rewarding.

Meditation is not only a way to integrate insights after a psychedelic journey, it is also a practical tool during the experience itself. By giving the mind a steady point of focus, meditation and breathwork can help guests remain comfortable, centered, and open throughout the session. For many, this makes the psychedelic journey smoother and more meaningful.

At the same time, psychedelics can transform meditation into something far more engaging, even for those who have struggled to connect with it in the past. By practicing both before and after macrodose sessions, guests learn how to use meditation and breathwork to reconnect with the sensations and mental states that psychedelics reveal. This combination supports long-lasting benefits and empowers participants to carry forward a personal routine that continues to enrich life well beyond the retreat.

For many guests focused on healthy aging, maintaining access to psilocybin beyond the retreat is an important part of a long-term wellness plan. Our in-depth mushroom cultivation course provides the knowledge and skills to grow your own mushrooms using readily available and legal supplies, making psilocybin practice safe, sustainable, and accessible at home.

As part of the 8-day program, the class is expanded into a comprehensive, hands-on curriculum that walks participants through every stage of cultivation. For those interested in brain health and extending healthspan, this course is more than a skill. It is a way to maintain consistent access to psilocybin’s potential neuroprotective and anti-inflammatory benefits, supporting resilience and vitality well into the future.

Learn the technique to extract DMT from legal, easy-to-source plant materials in this optional add-on class ($275). This course is especially valuable for guests who wish to incorporate the neuroprotective benefits of DMT into a long-term healthy aging plan. By leveraging DMT’s unique cognitive-protective features, participants can explore its potential role in extending healthspan and supporting brain vitality.

The class includes hands-on practice and purification techniques, giving guests the confidence and knowledge to safely and effectively continue this work at home.

Our fully integrated medical team is available on-site 24 hours a day throughout your retreat experience, ensuring your comfort and security. We recognize that older guests often bring unique medical considerations, including the use of daily medications and the added safety concerns that come with age. Our staff is well prepared to address these issues with care and attention, providing guidance and monitoring so that each participant can feel confident and supported throughout their retreat.

Our optional carefully designed intravenous (IV) therapies are crafted to elevate your wellness experience by delivering essential nutrients directly into your bloodstream. Whether you’re seeking a boost in energy, improved mental clarity, or enhanced recovery, our personalized IV drips can include key ingredients like Vitamin C, Glutathione, Magnesium, Zinc, Vitamin B-12, and Chromium. These nutrients work together to support immune function, detoxify the body, reduce fatigue, and promote mental focus, ensuring you feel revitalized from the inside out. By maximizing absorption, our IV therapies help restore balance and support overall well-being during your retreat, leaving you feeling your absolute best.

IV therapy sessions ($185-$220) can be scheduled on days when no psilocybin activities are planned. This ensures the treatments can be administered safely and effectively, allowing you to experience their full benefits without any interference.

Eleusinia’s Couples Package is designed to elevate your retreat experience with exclusive moments crafted for two. Enjoy a private picnic lunch, a romantic candlelit en-suite dinner, and the serenity of an additional couple’s massage. Dive deeper into your journey with a customized psilocybin macrodose session in your own private alcove together and a shared DMT experience, allowing you to connect on new levels. Our dedicated couple’s integration session offers space to reflect together, while the commitment renewal ceremony creates a meaningful way to celebrate and strengthen your bond.

Access 6 months of free membership to our exclusive online community of past retreat participants, where you can share your personal stories, experiences, and post-retreat progress. This network allows you to stay connected with fellow guests and Eleusinia team members from your retreat and also meet those who attended before you, expanding your involvement in the ever-growing Eleusinia family.

Participate in group discussions focused on post-retreat wellness practices, including dosing protocols, success stories, challenges, and improvements. Join a supportive environment for sharing, learning, and applying new knowledge to further your growth and goals.

Arrival & Orientation
Arrival day is focused on orientation and preparation. Guests arrive in the afternoon at Eleusinia’s private mountain estate, traveling by private shuttle from Mexico City. A welcome snack of tamales and champurrado sets the tone, followed by intake meetings with our medical team to ensure comfort and safety. The afternoon continues with a neuroscience-based presentation on psychedelics and a welcoming session with our curandera. This onboarding process provides both context and grounding, preparing guests for the psychedelic work that begins the very next day.

Psilocybin Macrodose 
The first macrodose day begins early with orientation, breathwork, and meditation to prepare for the psilocybin session ahead. Guests then take part in a six-hour outdoor psilocybin experience, held in private garden spaces designed for both safety and immersion in nature. Often described as a “mental marathon,” the session is deeply impactful and can be physically and emotionally tiring. The remainder of the day is set aside for quiet rest and recovery, allowing guests to fully absorb the experience.

DMT Session, Massage, Integration, and Mushroom Cultivation
This day begins with an educational orientation on DMT, including practical coaching on comfortable inhalation and vaporization techniques. Guests then follow personalized schedules that include a private DMT session, integration activities to process the previous day’s experiences, a massage, and a group meditation class. The first part of the mushroom cultivation class is held before dinner.

Recovery & TRE
This day is devoted to rest and reset, giving guests a pause from psychedelic work before continuing with deeper practices the following day. Optional IV therapy, one-on-one integration sessions, and an afternoon TRE (Tension & Trauma Release) class provide gentle support for recovery and relaxation. In the evening, the second part of the mushroom cultivation workshop continues, followed by a blindfolded “Dinner in the Dark,” a sensory exploration that enhances taste and presence while offering a unique communal experience

DMT Extraction Class & Temascal
The day begins with the first part of the DMT extraction class, introducing guests to the process of preparing DMT from natural plant sources. This is followed by a second DMT session, designed to be more personalized. Guests choose their preferred spot in the garden and are provided with their own vaporizer, giving them up to an hour to explore at their own pace. In the afternoon, the program shifts into restoration with a traditional Temascal (sweat lodge) ceremony, followed by time to unwind in our fireside indoor pool.

Second Psilocybin Macrodose
Similar in structure to the first macrodose day, the second psilocybin session serves as both a continuation and a refinement of the journey. Guests have the opportunity to adjust their dose and intentions, drawing on the insights and clarity gained from their first experience. Many find that this second session feels more vivid and rewarding as they become more comfortable navigating the psychedelic state. As before, the session takes place in private garden settings with attentive support throughout, followed by nourishing food and time to recover and reflect.

Excursions, Minidose, & Closing Ceremony
As the retreat moves toward completion, guests may choose to spend the morning on local excursions or remain onsite for a third DMT session, offered to participants in the extraction class. In the afternoon, a psilocybin minidose is paired with breathwork and meditation, providing a gentle way to integrate the week’s experiences. The day concludes with a celebratory cacao ceremony after dinner, a communal closing that marks the transition from retreat back into daily life.

Day 8 – Departure
A final breakfast is served at 8:00 AM, followed by a 9:30 AM shuttle departure back to Mexico City.

Less woo, more you.

Where elevated stays inspire sophisticated conversations and lasting connections.

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