5 Things To Know: How To Microdose Mushrooms For Migraines

#1. Migraine researchers at Yale don’t use microdoses in their studies.

Researchers running the Yale Medicine clinical trial for migraine do not use a microdose in their trial involving psilocybin and migraine. If you struggle with migraine, less frequent but slightly larger doses might be a better choice for you over the standard microdose schedule of dosing multiple times per week.

Clinical trials for migraine use amounts equivalent to 1.0 to 1.5 grams of dried mushrooms every 2 weeks. Given that the effects from this amount are usually equivalent to consuming an alcoholic beverage or consuming cannabis products, it is not likely to be a “crazy” experience. Keeping this in mind, it is important to recognize that different individuals have different tolerance levels and experiences.

The chart below describes the doses and their common terms.

psilocybin dosing

#2 Watch out for the rebound.

Psilocybin mushrooms can cause a rebound headache. Some people get a rebound headache after dosing. The intensity varies but getting a rebound headache after dosing may still result in less headaches overall. You will have to weigh the pros and cons for yourself.

#3. Get a good scale.

Owning a sensitive scale is important. To find a scale that is sensitive enough, try searching for a “jeweler’s scale”. If it is sensitive enough to measure in carats, then it will be sensitive enough for your purposes. Unfortunately, most food scales will not be sensitive enough to measure fractions of a gram so a specialty scale is necessary.

microdose mushrooms for migraine

Microdosing mushrooms for migraine requires precision. 

#4. Stay consistent.

Managing headaches with mushrooms works best with consistency. Specifically by growing your own supply, you guarantee that you will have no interruptions in treatment. There are various videos online explaining the cultivation process, including the series created by Eleusinia Retreat. If you attend one of our retreats, there is a comprehensive mushroom growing course.

The chart below describes how to use doses slightly larger than the typical microdose to manage migraine.

psilocybin pulse dose infographic

Psilocybin Dosing Cycle Infographic

#5. Get support if you dose higher.

The 1.0-1.5 grams typically used for migraine is unlikely to result in an intense experience. Some people benefit more from higher doses,  but it is not recommended that you go any higher without supervision and support. At the retreat, we coach you through various dose levels.

One Response

  1. Thank you for writing this guide, most sites discuss microdosing in relation to migraines but I’ve found bigger, less frequent doses to be more effective. I’m interested in trying this schedule next time I flare up.
    One quest: Is a maintenance dose the same amount as a pulse dose?

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