Psilocybin Retreat
Luxury All-Inclusive Psilocybin and DMT Retreat Program
The next level in psychedelic experiences.
Psilocybin opens many doors, but DMT opens the ones it cannot. At Eleusinia, both medicines work together as part of our comprehensive program to expand the map of possibility.
Psilocybin Retreat in Mexico
Experience a safe and immersive psychedelic journey, complete with expert guidance and medical support, at the only retreat offering a full-service med-spa, a mushroom cultivation workshop, and a DMT extraction class. Enjoy ultimate privacy in nature, combined with uncompromising luxury and comfort.
Sessions Completed
Private Retreat Center
For the Discerning Traveler
Think you know psychedelics? Not like this.
At Eleusinia, empowerment means putting the tools directly in your hands. You’ll gain a deep understanding of how psilocybin and DMT work in the brain, why they matter, and how to navigate these experiences safely. You’ll also learn practical skills like mushroom cultivation and DMT extraction.
We strip away the mystique and the gatekeeping that keep most people dependent on others.
After the retreat, the journey continues with weekly integration meetings and a vibrant online community.
This is about real mastery, and it lasts.
Until you’ve worked with both psilocybin and DMT, you’ve only glimpsed what’s possible.
At Eleusinia, each has its place, chosen for what it uniquely brings to the journey.
These experiences unfold not in crowded rooms, but in open-air gardens and private outdoor settings.
This isn’t one size fits all. It’s designed to meet you where you are, with the support and freedom to explore in a way that’s truly your own.
Together, these tools deepen the path in ways one alone cannot.
If “medical support” at past retreats meant little more than a safety net in case something went wrong, you’ve never really experienced true care.
At Eleusinia, our medical team isn’t tucked away in the background. They’re present, integrated, and proactive. They’re focused not just on safety, but on your comfort and depth of journey.
With a prescribing doctor and full support team on-site, you have the power of modern medicine alongside ancient tools.
That’s not just reassurance. That’s transformation made possible.
What Exactly Is A Neuroscience-Focused Psilocybin Retreat?
Eleusinia is a psilocybin retreat in Mexico that masterfully integrates modern research with a profound understanding of the effects of psychedelics on the brain. Here, you’ll encounter a unique blend of scientific rigor and consciousness exploration to unlock your full potential.
Psilocybin and DMT increase connectivity, communication, and synchrony between different brain regions. These remarkable substances serve as potent tools for elevating consciousness, deepening spirituality, and potentially shielding the brain and arteries from age-related illnesses like dementia and atherosclerosis. Additionally, they offer effective support for individuals managing chronic pain or mental health challenges by harnessing anti-inflammatory properties and promoting neuroplasticity.
In our retreats, we skillfully harmonize the worlds of science and tradition, ensuring you benefit from the best of both realms.
Who visits Eleusinia?
Is Eleusinia right for you?
Why choose a retreat in mexico?
With retreats popping up across the US, Europe, and the Caribbean, options aren't the issue - value is. Mexico just offers more. Rooted in tradition and supported by a thriving medical tourism infrastructure, it’s where our US-trained, licensed professionals have the greatest freedom to use every available tool - including medications and approaches not accessible elsewhere. The result? Better care, more effective support, and a stronger return on your investment.
welcoming guests also navigating
Not just a retreat: we're a working mushroom farm
Most retreats can’t tell you where their mushrooms come from. We can tell you exactly - because we grew them, from sterilized grain to the moment they're harvested.
Experience the only retreat that is also a fully functional mushroom farm and mycology center.
Mental Reset
At Eleusinia, about 30% of guests arrive seeking a mental reset, whether it's for overcoming a professional rut, handling major life changes, improving relationships, or exploring their inner consciousness.
Psychological Wellness
Approximately 40% of Eleusinia visitors seek to improve mental health, inspired by promising psychedelic clinical trials for depression, OCD, and addiction.
Pain Management
Approximately 30% of Eleusinia visitors utilize our expertise in chronic pain management, harnessing the untapped potential of psychedelics for physical relief.
join us for our live virtual open house
Check the calendar below to see when the next open house is happening, sign up to get the link, and easily add it to your schedule. We’d love to see you there.
Retreat Reviews
Sanjay PindoliaOctober 26, 2025 Eleusinia isn’t just a retreat. It’s a full-spectrum experience of science, ceremony, and soul. It’s truly something special. The location is beyond stunning, surrounded by nature that immediately puts you at ease. But what really makes it stand out is the team! Every single member of staff is friendly, compassionate, and genuinely cares. They tailor the experience to each individual, creating a space where it’s easy to trust, open up, and lean in fully. The program goes far beyond a mushroom ceremony. It’s a carefully designed, deeply human journey that stays with you long after you leave. Every detail, from the setting to the structure of each day feels intentional and supportive. This isn’t just a retreat; it’s an experience that leaves a lasting mark. Thomas AlbersonAugust 21, 2025 Eleusinia Retreat: A Life-Changing Journey for Chronic Pain and Personal Growth After years of battling chronic pain, I attended Eleusinia Retreat in Valle de Bravo, Mexico, seeking relief and to become a better husband, father, and person. The experience was transformative, offering far more than temporary respite, it reshaped my perspective in ways that continue to unfold. Set in the tranquil landscapes of Valle de Bravo, Eleusinia’s private, luxurious accommodations, spacious rooms with en-suite bathrooms create a serene backdrop. Small groups (4-6 participants) ensure an intimate, supportive vibe. The staff, led by facilitators with expertise in psychedelics and pain management, foster a grounded, science-based approach. The founder’s own chronic pain experience adds authenticity and empathy. The retreat’s guided psilocybin sessions, carefully dosed, were profound. They unraveled fear, love, pain, anger, and peace, helping me confront how chronic pain distanced me from my family. Facilitators offered gentle support, balancing spiritual and rational perspectives. Optional DMT workshops provided intense, complementary insights. Post-retreat, my pain is more manageable, and I’ve gained tools for ongoing relief. Days later, vivid dreams still process the experience, signaling lasting change. Eleusinia’s educational focus sets it apart. Workshops and psychedelic science taught me how to sustain my healing independently. Sessions on neuroscience were practical, not mystical, making the retreat uniquely empowering. Gourmet vegetarian meals, meditation spaces, nature walks, personalized playlists, and post-retreat support calls elevate the experience. The community bonded by shared struggles fostered authentic connections. Eleusinia is a worthwhile investment for anyone seeking relief from physical or emotional burdens. It’s professional, safe, and transformative, blending luxury, education, and empathy. My pain no longer defines me, and I’m a more present husband and father. For details, visit their site, my story is one of many. DNKAugust 13, 2025 This place is an absolute treasure - the location, the concept, the team, the experience - top notch. This is exactly the kind of place one needs to dive deep into self exploration/care/love without fear and hesitation. I’d recommend this place to anyone without hesitation and recall my memories of it with deep gratitude. Ryan M GrambartAugust 10, 2025 Knowledgeable, patient, and kind team in a beautiful, safe space — with fantastic food. bireshwarJune 16, 2025 The experience was magical, self-exploratory and spiritually awakening. Realizing there is more to life than life itself…Thanks to the beautiful ambience, amazing service, mouth watering food and the immense love and empathy of everyone working there. Jessica and Jay created an ultimate psilo experience. Jerry PriceMay 13, 2025 My experience at Eleusinia was something I will remember fondly for the rest of my life. The staff accepted us into their family and I accepted them into mine. My heart, mind and spirit will be forever grateful. James MenoMay 5, 2025 Having experimented with psilocybin as an adolescent and young adult, I viewed at it as something fun, scary, and most of all a powerful way to expand perspective. Now that I've been to Eleusinia, that hasn't changed haha! But, I would now add medicinal to my description of psychedelics. This experience was filled with uncomfortable moments for me, a lot happening in my head leading up to the experiences, and I don't think this is for everyone. The medicine was powerful; more than I ever experienced before. That said, IF you are ready or looking to shake up your life, this is for anyone. The staff and accommodations are outstanding. They will encourage you to explore and find the things you are there to work on, even if you don't know what they are. They guide without telling you what the exact path is, because it's different for everyone. They are there for you. Don't go with expectations, that's not how it works. If you are ready to let go a bit, this is the place. Not only through the medicine, but they take care of everything for you. I needed it, and I'm encouraged that these folks are genuinely helping people in a creative and unconventional way. Follow the love ;) Christa TApril 22, 2025 I recently attended a psilocybin mushroom retreat at Eleusinia, and the experience was nothing short of transformative. From the moment I arrived, there was a palpable sense of calm. The facilitators were experienced, deeply compassionate, and incredibly grounded. They provided an environment that felt not just safe, but sacred. Every aspect of the retreat was thoughtfully curated to support deep inner work. The psilocybin ceremony itself was guided with respect and reverence. Surrounded by nature, I was able to navigate profound emotional releases and an overwhelming sense of interconnectedness. Integration was a major focus of the retreat, and I appreciated how much attention was given to helping us bring our insights back into daily life, including one-on-one coaching. This retreat wasn’t just a psychedelic experience — it was a deep dive into healing, self-acceptance, and transformation. I can’t recommend it enough. Debbie LeeApril 6, 2025 I have been to Eleusinia twice and I plan to make this a return regularly. The staff, accommodations and the food is excellent. It is a life changing experience. Sergey AApril 2, 2025 It’s been seven months since I visited Eleusinia, and the amount of positive change I’ve been able to create in my life since then is unbelievable. It’s as if I’ve gained a new level of self-awareness, allowing me to see myself from an outside perspective and make meaningful improvements. The retreat itself is exceptional—a perfect setting for a profound, life-changing experience like psychedelics. The environment is peaceful and thoughtfully designed to put your mind at ease, allowing for deep introspection and transformation. The food was outstanding, the staff was incredibly attentive and supportive, and the accommodations were both luxurious and cozy, making the entire experience feel safe and comfortable. I’ve had many different experiences in my life, but this one stands out as one of the most impactful. I especially appreciated their science-based approach, free from any unnecessary mysticism or rituals. It’s a place where you can focus purely on your journey with confidence, knowing you are in the best hands. If you’re considering a retreat like this, I can’t recommend Eleusinia enough. Whether you’re looking for personal growth, healing, or just a new perspective on life, this is the ideal place to do it. It’s an experience that stays with you long after you leave, shaping your mindset in ways you never imagined. I’m deeply grateful for my time there, and I encourage anyone seeking meaningful change to take that step—you won’t regret it.Google rating score: 4.9 of 5, based on 94 reviews
Less woo, more you.
Where elevated stays inspire sophisticated conversations and lasting connections.
Our Articles
The Eleusinia Story
Jessica established Eleusinia, a psilocybin retreat in Mexico, after finding lasting relief from Hemicrania Continua - a debilitating headache condition - through psilocybin treatment. Located in Mexico, Eleusinia embodies her vision of an authentic cultural psychedelic retreat experience, blending the latest neuroscience with high standards for personalized care, comfortable accommodations, and balanced wellness support.
Want to hear real retreat stories from real guests? Check out our podcast with over 60 guest interviews detailing their experiences at our psilocybin retreat in Mexico.
We value your privacy
At Eleusinia Retreat, we are committed to protecting your privacy. To reflect the discretion we offer and the caliber of our guests, we maintain a firm no-photography policy and never share identifiable photos on social media.