Psilocybin Retreat

Luxury All-Inclusive Psilocybin and DMT Retreat Program 

The next level in psychedelic experiences.

Psilocybin opens many doors, but DMT opens the ones it cannot. At Eleusinia, both medicines work together as part of our comprehensive program to expand the map of possibility.

Psilocybin Retreat in Mexico

Experience a safe and immersive psychedelic journey, complete with expert guidance and medical support, at the only retreat offering a full-service med-spa, a mushroom cultivation workshop, and a DMT extraction class. Enjoy ultimate privacy in nature, combined with uncompromising luxury and comfort.

3,500+

Sessions Completed

100-Acre

Private Retreat Center

#1 Choice

For the Discerning Traveler

mycology class
The Next Level in Empowerment

Think you know psychedelics? Not like this.

At Eleusinia, empowerment means putting the tools directly in your hands. You’ll gain a deep understanding of how psilocybin and DMT work in the brain, why they matter, and how to navigate these experiences safely. You’ll also learn practical skills like mushroom cultivation and DMT extraction.

We strip away the mystique and the gatekeeping that keep most people dependent on others.

After the retreat, the journey continues with weekly integration meetings and a vibrant online community.

This is about real mastery, and it lasts.

DMT Station
The Next Level in Choices

Until you’ve worked with both psilocybin and DMT, you’ve only glimpsed what’s possible.

At Eleusinia, each has its place, chosen for what it uniquely brings to the journey.

These experiences unfold not in crowded rooms, but in open-air gardens and private outdoor settings.

This isn’t one size fits all. It’s designed to meet you where you are, with the support and freedom to explore in a way that’s truly your own.

Together, these tools deepen the path in ways one alone cannot.

medical staff
The Next Level in Medical Support

If “medical support” at past retreats meant little more than a safety net in case something went wrong, you’ve never really experienced true care.

At Eleusinia, our medical team isn’t tucked away in the background. They’re present, integrated, and proactive. They’re focused not just on safety, but on your comfort and depth of journey.

With a prescribing doctor and full support team on-site, you have the power of modern medicine alongside ancient tools.

That’s not just reassurance. That’s transformation made possible.

What Exactly Is A Neuroscience-Focused Psilocybin Retreat?

Eleusinia is a psilocybin retreat in Mexico that masterfully integrates modern research with a profound understanding of the effects of psychedelics on the brain. Here, you’ll encounter a unique blend of scientific rigor and consciousness exploration to unlock your full potential.

Psilocybin and DMT increase connectivity, communication, and synchrony between different brain regions. These remarkable substances serve as potent tools for elevating consciousness, deepening spirituality, and potentially shielding the brain and arteries from age-related illnesses like dementia and atherosclerosis. Additionally, they offer effective support for individuals managing chronic pain or mental health challenges by harnessing anti-inflammatory properties and promoting neuroplasticity.

In our retreats, we skillfully harmonize the worlds of science and tradition, ensuring you benefit from the best of both realms.

Is Eleusinia right for you?

Are you ready for the shuffle?
Think of your mental models as a deck of cards. Over time, they stack into rigid patterns that shape how you see and respond to the world.
Are you ready to take charge?
Eleusinia is for those who want dominion and mastery over their journey. Learn the science and the tools to master your psychedelic path.
Are you ready to unlearn?
We challenge psychedelic norms, rejecting hype and dogma with practical, evidence-based methods designed for real results and lasting change.

Why choose a retreat in mexico?

With retreats popping up across the US, Europe, and the Caribbean, options aren't the issue - value is. Mexico just offers more. Rooted in tradition and supported by a thriving medical tourism infrastructure, it’s where our US-trained, licensed professionals have the greatest freedom to use every available tool - including medications and approaches not accessible elsewhere. The result? Better care, more effective support, and a stronger return on your investment.

welcoming guests also navigating

Not just a retreat: we're a working mushroom farm

Most retreats can’t tell you where their mushrooms come from. We can tell you exactly - because we grew them, from sterilized grain to the moment they're harvested.

Experience the only retreat that is also a fully functional mushroom farm and mycology center.

Mental Reset

At Eleusinia, about 30% of guests arrive seeking a mental reset, whether it's for overcoming a professional rut, handling major life changes, improving relationships, or exploring their inner consciousness.

Psychological Wellness

Approximately 40% of Eleusinia visitors seek to improve mental health, inspired by promising psychedelic clinical trials for depression, OCD, and addiction.

Pain Management

Approximately 30% of Eleusinia visitors utilize our expertise in chronic pain management, harnessing the untapped potential of psychedelics for physical relief.

join us for our live virtual open house

Check the calendar below to see when the next open house is happening, sign up to get the link, and easily add it to your schedule. We’d love to see you there.

Less woo, more you.

Where elevated stays inspire sophisticated conversations and lasting connections. 

Our Articles

jessicak

The Eleusinia Story

Jessica established Eleusinia, a psilocybin retreat in Mexico, after finding lasting relief from Hemicrania Continua - a debilitating headache condition - through psilocybin treatment. Located in Mexico, Eleusinia embodies her vision of an authentic cultural psychedelic retreat experience, blending the latest neuroscience with high standards for personalized care, comfortable accommodations, and balanced wellness support.

Want to hear real retreat stories from real guests? Check out our podcast with over 60 guest interviews detailing their experiences at our psilocybin retreat in Mexico.

We value your privacy

At Eleusinia Retreat, we are committed to protecting your privacy. To reflect the discretion we offer and the caliber of our guests, we maintain a firm no-photography policy and never share identifiable photos on social media.

Experience shared growth and connection at Eleusinia, where families deepen bonds and foster lasting understanding together.